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Sequencher Connections is now more flexible and customizable. Existing Connections sessions can be reopened and have new sequences added to them. Your Connections sessions can be renamed to reflect your project. There are now more options for adding channels to a Connections session and each channel can also be named
When you are working with NGS data, whether it is DNA-Seq or RNA-Seq, you will want the best algorithms. For speed, BWA-MEM is able to give you reference-guided alignments with genome sizes up to human genome size and beyond. Despite its speed, it still has a small memory requirement. For a feature-rich program able to deal with regular sequences, spliced sequences, methylation-tolerant alignments, SNP-tolerant alignments, and RNA-I tolerant alignments, then GSNAP is the algorithm of choice.
SNP Detection Sequencher has several powerful tools to help you detect mutations and SNPs in your DNA sequences. You can use Sequencher for comparative sequence alignments among a group of sequences, or to compare 1 or more sequences to a Reference Sequence. Sequencher’s Call Secondary Peaks... function analyzes all of your sequences for potential heterozygotes. It’s easy to control the stringency that defines a heterozygote.
RNA-Seq: Expanded Cufflinks suite with the addition of Cuffquant and Cuffnorm. A unique Conditions and Replicates Editor for Cuffdiff and Cuffnorm.
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